Hydrodynamic instabilities, waves and turbulence in spreading epithelia.

  title={Hydrodynamic instabilities, waves and turbulence in spreading epithelia.},
  author={C Blanch-Mercader and Jaume Casademunt},
  journal={Soft matter},
  volume={13 38},
We present a hydrodynamic model of spreading epithelial monolayers described as polar viscous fluids, with active contractility and traction on a substrate. The combination of both active forces generates an instability that leads to nonlinear traveling waves, which propagate in the direction of polarity with characteristic time scales that depend on contact forces. Our viscous fluid model provides a comprehensive understanding of a variety of observations on the slow dynamics of epithelial… CONTINUE READING
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