Hydrodynamic Delivery of Chitosan-Folate-DNA Nanoparticles in Rats with Adjuvant-Induced Arthritis

Abstract

50 kDa chitosan was conjugated with folate, a specific tissue-targeting ligand. Nanoparticles such as chitosan-DNA and folate-chitosan-DNA were prepared by coacervation process. The hydrodynamic intravenous injection of nanoparticles was performed in the right posterior paw in normal and arthritic rats. Our results demonstrated that the fluorescence… (More)
DOI: 10.1155/2011/148763

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Cite this paper

@inproceedings{Shi2011HydrodynamicDO, title={Hydrodynamic Delivery of Chitosan-Folate-DNA Nanoparticles in Rats with Adjuvant-Induced Arthritis}, author={Qin Shi and Huijie Wang and Covi Tran and Xingping Qiu and Françoise M Winnik and Xiaoling Zhang and Ke-Rong Dai and Mohamed Benderdour and Julio Cesar Bastos Fernandes}, booktitle={Journal of biomedicine & biotechnology}, year={2011} }