Hydrocortisone-induced hypertension in men. The role of cardiac output.

  title={Hydrocortisone-induced hypertension in men. The role of cardiac output.},
  author={Marinis Pirpiris and S T Yeung and Elizabeth M. Dewar and Garry L Jennings and Judith Ann Whitworth},
  journal={American journal of hypertension},
  volume={6 4},
In previous studies we have shown that administration of 200 mg/day hydrocortisone (cortisol) to normal subjects raises blood pressure and cardiac output, with no change in total peripheral resistance or resting forearm vascular resistance. We have tested the hypothesis that this rise in cardiac output is essential for the rise in blood pressure (BP). Six normal volunteer men, aged 22 to 34 years, took part in two studies of 10 days, in random order, at least 4 weeks apart. Placebo (Study A) or… CONTINUE READING