Hydrocephalus-induced changes in the composition of cerebrospinal fluid.

  title={Hydrocephalus-induced changes in the composition of cerebrospinal fluid.},
  author={Marc R Del Bigio},
  volume={25 3},
Studies reporting the composition of cerebrospinal fluid obtained from hydrocephalic humans have been critically reviewed. Hydrocephalus-induced alterations in the cerebrospinal fluid concentrations of neurotransmitters and peptide neuromodulators, products of glycolysis and nucleotide metabolism, neural cell-derived proteins and enzymes, and serum-derived proteins have been documented. The data are interpreted with reference to experimental studies. The reported changes suggest that in the… CONTINUE READING