Hydraulic permeability of multilayered collagen gel scaffolds under plastic compression-induced unidirectional fluid flow.

@article{Serpooshan2013HydraulicPO,
  title={Hydraulic permeability of multilayered collagen gel scaffolds under plastic compression-induced unidirectional fluid flow.},
  author={Vahid Serpooshan and T M Khayat Quinn and Naser Muja and Showan N. Nazhat},
  journal={Acta biomaterialia},
  year={2013},
  volume={9 1},
  pages={4673-80}
}
Under conditions of free fluid flow, highly hydrated fibrillar collagen gels expel fluid and undergo gravity driven consolidation (self-compression; SC). This process can be accelerated by the application of a compressive stress (plastic compression; PC) in order to generate dense collagen scaffolds for tissue engineering. To define the microstructural evolution of collagen gels under PC, this study applied a two-layer micromechanical model that was previously developed to measure hydraulic… CONTINUE READING