Hydration of vinyl ether groups by unsaturated glycoside hydrolases and their role in bacterial pathogenesis.

@article{Hashimoto2007HydrationOV,
  title={Hydration of vinyl ether groups by unsaturated glycoside hydrolases and their role in bacterial pathogenesis.},
  author={Wataru Hashimoto and Takafumi Itoh and Yukie Maruyama and Bunzo Mikami and Kousaku Murata},
  journal={International microbiology : the official journal of the Spanish Society for Microbiology},
  year={2007},
  volume={10 4},
  pages={233-43}
}
Many pathogenic microorganisms invade mammalian and/or plant cells by producing polysaccharide-degrading enzymes (lyases and hydrolases). Mammalian glycosaminoglycans and plant pectins that form part of the cell surface matrix are typical targets for these microbial enzymes. Unsaturated glycoside hydrolase catalyzes the hydrolytic release of an unsaturated uronic acid from oligosaccharides, which are produced through the reaction of matrix-degrading polysaccharide lyase. This enzymatic ability… CONTINUE READING
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