Hydra regeneration and epitheliopeptides

@article{Fujisawa2003HydraRA,
  title={Hydra regeneration and epitheliopeptides},
  author={Toshitaka Fujisawa},
  journal={Developmental Dynamics},
  year={2003},
  volume={226}
}
  • T. Fujisawa
  • Published 1 February 2003
  • Biology
  • Developmental Dynamics
Hydra has been well known for over 200 years for its remarkable regenerative capacity. In addition to small pieces excised from the body, reaggregates of dissociated single cells can also regenerate. Although the cellular events involved in the regeneration process have been well characterized, the underlying molecular mechanisms are yet to be uncovered. Recently, however, transcription factors and signaling molecules, both proteins and short peptides, have been identified and their role… 

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Hydra Peptide Project 1993–2007

  • T. Fujisawa
  • Biology
    Development, growth & differentiation
  • 2008
A systematic screening of peptide signaling molecules in Hydra magnipapillata (the Hydra Peptide Project) was launched in 1993 and at least the first phase of the project ended in 2007, and many novel neuropeptides were identified.

Subcellular localization of the epitheliopeptide, Hym-301, in hydra

The intracellular localization of Hym-301 in hydra is examined by using immunohistochemical and immunogold electron-microscopic analyses and it is found that the pattern of distribution of mature peptide is slightly different from that of its mRNA, and that it is stored in vesicles located adjacent to the cell membrane.
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  • Biology, Chemistry
    BioEssays : news and reviews in molecular, cellular and developmental biology
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