Hybridization assay of hepatitis B virus by QCM peptide nucleic acid biosensor.

@article{Yao2008HybridizationAO,
  title={Hybridization assay of hepatitis B virus by QCM peptide nucleic acid biosensor.},
  author={Chunyan Yao and Tangyou Zhu and Jin Tang and Rong Y Wu and Qinghai Chen and Ming Chen and Bo Zhang and Junfu Huang and Weiling Fu},
  journal={Biosensors & bioelectronics},
  year={2008},
  volume={23 6},
  pages={879-85}
}
Although the analyses of HBV genomic DNA have traditionally been performed with commercial techniques, the high cost and long time consumed have hindered their applications in routinely diagnosis and prognosis of infection. We construct peptide nucleic acid (PNA) piezoelectric biosensor for real-time monitoring of hybridization of hepatitis B virus (HBV) genomic DNA. The PNA probe can combine to target DNA sequences more effectively and specifically than a DNA probe. The PNA probe was designed… CONTINUE READING