Hybrid methods for macromolecular structure determination: experiment with expectations.


Studies of large and heterogeneous macromolecules often yield low-resolution data that alone does not suffice to build accurate atomic models. Adding information from molecular simulation or other structure prediction methods can lead to models with significantly better quality. Different strategies are discussed to combine experimental data with results… (More)
DOI: 10.1016/j.sbi.2015.02.016


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