Hybrid method for the chemical master equation

  title={Hybrid method for the chemical master equation},
  author={Andreas Hellander and Per L{\"o}tstedt},
  journal={J. Comput. Physics},
The chemical master equation is solved by a hybrid method coupling a macroscopic, deterministic description with a mesoscopic, stochastic model. The molecular species are divided into one subset where the expected values of the number of molecules are computed and one subset with species with a stochastic variation in the number of molecules. The macroscopic equations resemble the reaction rate equations and the probability distribution for the stochastic variables satisfy a master equation… CONTINUE READING