Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains

@article{Wang1999HybridHA,
  title={Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains},
  author={Chun Wang and Russell J. Stewart and Jindřich Kope{\vc}ek},
  journal={Nature},
  year={1999},
  volume={397},
  pages={417-420}
}
Stimuli-sensitive polymer hydrogels, which swell or shrink in response to changes in the environmental conditions, have been extensively investigated and used as ‘smart’ biomaterials and drug-delivery systems, . Most of these responsive hydrogels are prepared from a limited number of synthetic polymers and their derivatives, such as copolymers of (meth)acrylic acid, acrylamide and N-isopropyl acrylamide. Water-soluble synthetic polymers have also been crosslinked with molecules of biological… CONTINUE READING