Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control

@article{Teixeira2006HybridEF,
  title={Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control},
  author={Ana P. Teixeira and Carlos Alves and Paula M. Alves and Manuel J. T. Carrondo and Rui Oliveira},
  journal={BMC Bioinformatics},
  year={2006},
  volume={8},
  pages={30 - 30}
}
The progress in the "-omic" sciences has allowed a deeper knowledge on many biological systems with industrial interest. This knowledge is still rarely used for advanced bioprocess monitoring and control at the bioreactor level. In this work, a bioprocess control method is presented, which is designed on the basis of the metabolic network of the organism under consideration. The bioprocess dynamics are formulated using hybrid rigorous/data driven systems and its inherent structure is defined by… CONTINUE READING
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Applications of metabolic modeling to drive bioprocess development for the production of value-added chemicals

  • R Mahadevan, AP Burgard, I Famili, S Van Dien, CH Schilling
  • Biotech and Bioprocess Eng
  • 2005
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