Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.

@article{Rampa2011HybridbasedML,
  title={Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.},
  author={Angela Rampa and Federica Belluti and Silvia Gobbi and Alessandra Bisi},
  journal={Current topics in medicinal chemistry},
  year={2011},
  volume={11 22},
  pages={
          2716-30
        }
}
Progresses in medicinal chemistry over the last few years have focused on the design and synthesis of hybrid compounds, molecules encompassing in a single scaffold two pharmacophores from known entities endowed with well established biological activities. The interest in this topic is related to the increasing emphasis on the identification of the different… CONTINUE READING