Hybrid artificial neural network segmentation and classification of dynamic contrast-enhanced MR imaging (DEMRI) of osteosarcoma.

@article{Glass1998HybridAN,
  title={Hybrid artificial neural network segmentation and classification of dynamic contrast-enhanced MR imaging (DEMRI) of osteosarcoma.},
  author={John O. Glass and Wilburn E. Reddick},
  journal={Magnetic resonance imaging},
  year={1998},
  volume={16 9},
  pages={1075-83}
}
The evaluation of pediatric osteosarcoma has suffered from the lack of an accurate imaging measure of response. One major problem is that osteosarcoma do not shrink in response to chemotherapy; instead, viable tumor is replaced by necrotic tissue. Currently available techniques that use dynamic contrast-enhanced magnetic resonance imaging to quantitatively evaluate tumor response fail to assess the percentage of necrosis. At present, histopathologic evaluation of resected tissue is the only… CONTINUE READING

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