Hybrid PGS-PCL microfibrous scaffolds with improved mechanical and biological properties.

@article{Sant2011HybridPM,
  title={Hybrid PGS-PCL microfibrous scaffolds with improved mechanical and biological properties.},
  author={Shilpa Sant and Chang Mo Hwang and Sang-Hoon Lee and Ali Khademhosseini},
  journal={Journal of tissue engineering and regenerative medicine},
  year={2011},
  volume={5 4},
  pages={283-91}
}
Poly(glycerol sebacate) (PGS) is a biodegradable elastomer that has generated great interest as a scaffold material due to its desirable mechanical properties. However, the use of PGS in tissue engineering is limited by difficulties in casting micro- and nanofibrous structures, due to high temperatures and vacuum required for its curing and limited solubility of the cured polymer. In this paper, we developed microfibrous scaffolds made from blends of PGS and poly(ε-caprolactone) (PCL) using a… CONTINUE READING