Hyaluronidase To Enhance Nanoparticle-Based Photodynamic Tumor Therapy.

  title={Hyaluronidase To Enhance Nanoparticle-Based Photodynamic Tumor Therapy.},
  author={Hua Gong and Yu Chao and Jian Xiang and Xiguang Han and Guosheng Song and Liangzhu Feng and Jingjing Liu and Guangbao Yang and Qian Chen and Zhuang Liu},
  journal={Nano letters},
  volume={16 4},
Photodynamic therapy (PDT) is considered as a safe and selective way to treat a wide range of cancers as well as nononcological disorders. However, as oxygen is required in the process of PDT, the hypoxic tumor microenvironment has largely limited the efficacy of PDT to treat tumors especially those with relatively large sizes. To this end, we uncover that… CONTINUE READING