Hyaluronic acid induced hyaluronic acid binding protein phosphorylation and inositol triphosphate formation in lymphocytes.

@article{Rao1996HyaluronicAI,
  title={Hyaluronic acid induced hyaluronic acid binding protein phosphorylation and inositol triphosphate formation in lymphocytes.},
  author={Chamallamudi Mallikajuna Rao and Tushar B. Deb and Kasturi Datta},
  journal={Biochemistry and molecular biology international},
  year={1996},
  volume={40 2},
  pages={327-37}
}
In this report, the role of 34 kDa HA-binding protein in hyaluronic acid-induced cellular signalling in lymphocytes has been examined. The binding of 125I-HA to lymphocytes in vivo was found to be inhibited by pre-incubation of the cells with anti-34 kDa HA-binding protein antibodies, thus confirming 34 kDa HA-binding protein as the specific HA-receptor in lymphocytes. This observation was substantiated by anti-34 kDa HA-binding protein antibodies immunoblotting and 125I-HA ligand blotting of… CONTINUE READING
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