Hyaluronic acid concentration in postmenopausal facial skin after topical estradiol and genistein treatment: a double-blind, randomized clinical trial of efficacy.

@article{Patriarca2013HyaluronicAC,
  title={Hyaluronic acid concentration in postmenopausal facial skin after topical estradiol and genistein treatment: a double-blind, randomized clinical trial of efficacy.},
  author={Marisa Teresinha Patriarca and Andr{\'e}a Regina Barbosa de Moraes and Helena Bociane Nader and Val{\'e}ria Petri and Jo{\~a}o Roberto Maciel Martins and Regina C{\'e}lia Teixeira Gomes and Jos{\'e} M. Soares},
  journal={Menopause},
  year={2013},
  volume={20 3},
  pages={336-41}
}
OBJECTIVE The aim of this work was to compare the effects of estradiol and genistein treatment on hyaluronic acid (HA) concentration in postmenopausal facial skin. METHODS In this study, 30 postmenopausal women were evaluated in a prospective, randomized, double-blind trial. The volunteers were postmenopausal women treated in the Gynecology Department of the Federal University of São Paulo. The participants were divided into two groups: group E, treated with 0.01% 17β-estradiol gel (n = 15… CONTINUE READING