Hyaluronic acid-bearing lipoplexes: physico-chemical characterization and in vitro targeting of the CD44 receptor.

Abstract

The mechanism by which hyaluronic acid (HA)-bearing lipoplexes target the A549 lung cancer cell line was evaluated. For this purpose, cationic liposomes targeting the CD44 receptor were designed thanks to the incorporation in their composition of a conjugate between high molecular weight HA and the lipid DOPE (HA-DOPE). Liposomes containing HA-DOPE were… (More)
DOI: 10.1016/j.jconrel.2012.07.015

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@article{Wojcicki2012HyaluronicAL, title={Hyaluronic acid-bearing lipoplexes: physico-chemical characterization and in vitro targeting of the CD44 receptor.}, author={Am{\'e}lie Dufa{\"{y} Wojcicki and Herv{\'e} Hillaireau and Tha{\'i}s Leite Nascimento and Silvia Arpicco and M Taverna and Sandy Ribes and Micka{\"{e}l Bourge and Val{\'e}rie Nicolas and Am{\'e}lie Bochot and Christine Vauthier and Nicolas Tsapis and Elias Fattal}, journal={Journal of controlled release : official journal of the Controlled Release Society}, year={2012}, volume={162 3}, pages={545-52} }