Hyaluronic acid-based nanocarriers for intracellular targeting: interfacial interactions with proteins in cancer.

@article{Choi2012HyaluronicAN,
  title={Hyaluronic acid-based nanocarriers for intracellular targeting: interfacial interactions with proteins in cancer.},
  author={Ki Young Choi and Gurusamy Saravanakumar and Jae H Park and K. M. Park},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2012},
  volume={99},
  pages={82-94}
}
The therapeutic efficacy of most drugs is greatly depends on their ability to cross the cellular barrier and reach their intracellular target sites. To transport the drugs effectively through the cellular membrane and to deliver them into the intracellular environment, several interesting smart carrier systems based on both synthetic or natural polymers have been designed and developed. In recent years, hyaluronic acid (HA) has emerged as a promising candidate for intracellular delivery of… CONTINUE READING

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