Hyaluronic acid-based carbon dots for efficient gene delivery and cell imaging

@inproceedings{Wang2017HyaluronicAC,
  title={Hyaluronic acid-based carbon dots for efficient gene delivery and cell imaging},
  author={Hai-Jiao Wang and Ji Zhang and Yan-Hong Liu and Tian-Ying Luo and Xi He Xi He and Xiaoqi Yu},
  year={2017}
}
A strategy that uses hyaluronic acid (HA) as a carbon source and polyethylenimine (PEI) as a passivant to construct carbon dots (HA-Cds) was proposed. The synthetic method is simple and green and no additive was required. These carbon dots could emit strong blue fluorescence under UV light. FT-IR and 1H NMR spectra confirmed that part of characteristic residues of HA and PEI remained in the HA-Cds structure. These materials had much lower cytotoxicity than PEI and high serum tolerance. Up to 50… CONTINUE READING

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