Hyaluronic acid and wound healing.

@article{Neuman2015HyaluronicAA,
  title={Hyaluronic acid and wound healing.},
  author={Manuela G. Neuman and Radu M. Nanau and Loida Oru{\~n}a-Sanchez and Gabriel Coto},
  journal={Journal of pharmacy \& pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques},
  year={2015},
  volume={18 1},
  pages={
          53-60
        }
}
  • M. Neuman, R. Nanau, Gabriel Coto
  • Published 29 January 2015
  • Medicine, Biology
  • Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
BACKGROUND We developed an experimental model of ethanol-induced dermatotoxicity and hepatocytoxicity using normal human keratinocytes and normal human hepatocytes that preserve inducible cytochrome p450 activities. The original work was described in several articles. The objective of this study was to determine whether hyaluronic acid attenuates skin necrosis, and to further clarify its uses in wound repair in humans, animal models and in vitro studies. METHODS We performed a systematic… 
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TLDR
The performance of this innovative hybrid cooperative complex of high- and low-molecular-weight hyaluronan in a novel in vitro HaCaT (immortalized human keratinocytes)/HDF (human dermal fibroblast) co-culture model to assess its ability to repair skin tissue lesions was investigated.
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TLDR
Topical application of HA film to perianal wounds improves the wound healing rate in a rat model, suggesting a potential benefit ofHA film application in promoting wound healing after anal surgery in humans.
Comparison of Pathologic Effects of Hyaluronic Acid And Collagenase on Wound Healing of Rabbit Ear Cartilage Tissue
TLDR
The findings of the present experimental study indicate that neither hyaluronic acid nor collagenase has any promoting effect on wound healing of ear cartilage tissue.
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Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals
TLDR
The biological effect of HA on the skin level and its potential adverse effects are discussed and some available cosmetic products containing HA have been identified from the brand portfolio of most known manufacturers and their composition was evaluated.
Effects of a Catechol-Functionalized Hyaluronic Acid Patch Combined with Human Adipose-Derived Stem Cells in Diabetic Wound Healing
TLDR
The combination of HA-CA and ADSCs provided synergistic wound healing effects by maximizing paracrine signaling and angiogenesis via the PI3K/AKT pathway and might represent a novel strategy for the treatment of DBW.
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