Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin α(v)β(3) interaction.

Abstract

Cell migration is the hallmark of cancer regulating anchorage independent growth and invasiveness of tumor cells. Hyaluronan (HA), an ECM polysaccharide is shown to regulate this process. In the present report, we demonstrated, supplementation of purified recombinant hyaluronan binding protein 1(HABP1/p32/gC1qR) from human fibroblast cDNA enhanced migration… (More)
DOI: 10.1016/j.cellsig.2011.04.009

Topics

Cite this paper

@article{Prakash2011HyaluronanbindingP1, title={Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin α(v)β(3) interaction.}, author={Mansi Prakash and Smita S. Kale and Ilora Ghosh and Gopal Chandra Kundu and K. Misra Datta}, journal={Cellular signalling}, year={2011}, volume={23 10}, pages={1563-77} }