Hxk2 regulates the phosphorylation state of Mig1 and therefore its nucleocytoplasmic distribution.

@article{Ahuatzi2007Hxk2RT,
  title={Hxk2 regulates the phosphorylation state of Mig1 and therefore its nucleocytoplasmic distribution.},
  author={Deifilia Ahuatzi and Alberto Riera and Rafael Pel{\'a}ez and Pilar Herrero and Fernando Moreno},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 7},
  pages={4485-93}
}
Mig1 and Hxk2 are two major mediators of glucose repression in Saccharomyces cerevisiae. However, the mechanism by which Hxk2 participates in the glucose repression signaling pathway is not completely understood. Recently, it has been demonstrated that Hxk2 interacts with Mig1 to generate a repressor complex located in the nucleus of S. cerevisiae. However, the mechanism by which Mig1 favors the presence of Hxk2 in the nucleus is not clear, and the function of Hxk2 at the nuclear repressor… CONTINUE READING

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