Hutchinson-Gilford Progeria Syndrome: Its Presentation in F. Scott Fitzgerald’s Short Story ‘The Curious Case of Benjamin Button’ and Its Oral Manifestations

@article{Maloney2009HutchinsonGilfordPS,
  title={Hutchinson-Gilford Progeria Syndrome: Its Presentation in F. Scott Fitzgerald’s Short Story ‘The Curious Case of Benjamin Button’ and Its Oral Manifestations},
  author={William James Maloney},
  journal={Journal of Dental Research},
  year={2009},
  volume={88},
  pages={873 - 876}
}
  • W. Maloney
  • Published 1 October 2009
  • Medicine
  • Journal of Dental Research
Hutchinson-Gilford Progeria Syndrome (HGPS) was first documented in the medical literature in 1886. A HGPS patient has the physical characteristics and appearances of an elderly individual. In 1921, F. Scott Fitzgerald published a short story entitled ‘The Curious Case of Benjamin Button’. The main character of Fitzgerald’s fictional work is born with a very rare condition in which he looks like an elderly person. The main difference between the fictional individual and individuals with HGPS is… 
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TLDR
There has been no typical case of progeria reported in British literature since the original two cases, although Parsons (1949) and IsIIt IC 4 LLc 4JJ ACJ (YI ) l& Usc a typical progerian skull.
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TLDR
Patients can be subdivided in patients with classical HGPS, which follows an autosomal dominant pattern of inheritance, all cases representing spontaneous mutations, and in non‐classical progeria, in whom growth can be less retarded, scalp hair remains present for a longer time, lipodystrophy is more slowly progressive, osteolysis is more expressed except in the face, and survival well into adulthood.
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TLDR
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TLDR
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TLDR
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TLDR
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