Huperzine A: Is it an Effective Disease-Modifying Drug for Alzheimer’s Disease?

  title={Huperzine A: Is it an Effective Disease-Modifying Drug for Alzheimer’s Disease?},
  author={Zhong-Ming Qian and Ya Ke},
  booktitle={Front. Aging Neurosci.},
Alzheimer's disease (AD) is a progressive neurodegenerative disorder for which there is no cure. Huperzine A (HupA) is a natural inhibitor of acetylcholinesterase (AChE) derived from the Chinese folk medicine Huperzia serrata (Qian Ceng Ta). It is a licensed anti-AD drug in China and is available as a nutraceutical in the US. A growing body of evidence has demonstrated that HupA has multifaceted pharmacological effects. In addition to the symptomatic, cognitive-enhancing effect via inhibition… CONTINUE READING
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