• DOI:10.1016/S0140-6736(07)60111-1
Corpus ID: 46151626

Huntington's disease

@article{Walker2007HuntingtonsD,
  title={Huntington's disease},
  author={F. Walker},
  journal={The Lancet},
  year={2007},
  volume={369},
  pages={218-228}
}

• F. Walker
• Published 2007
• Medicine
• The Lancet

Huntington's disease may present at any age, but most typically manifests between the ages of 35 and 45 years as a slowly progressive neurodegenerative movement disorder with cognitive and behavioral impairment. It is an autosomal-dominant disorder that has a substantial impact on family structure and dynamics in terms of providing care for affected family members and, for the offspring of an affected parent, dealing with at-risk status. Therapy that slows the progressive neuronal dysfunction… Expand