Hungary 5-hydroxytryptamine is a mediator of 4-aminopyridine induced contractions in porcine and human isolated coronary arteries

@inproceedings{Kun2000Hungary5I,
  title={Hungary 5-hydroxytryptamine is a mediator of 4-aminopyridine induced contractions in porcine and human isolated coronary arteries},
  author={Attila Kun and J{\'a}nos Pataricza and Ir{\'e}n Krass{\'o}i and Mikl{\'o}s Opincariu and J{\'a}nos Sz{\'e}csi and Julius Gy. Papp},
  year={2000}
}
The effect of 4-aminopyridine (4-AP), a known inhibitor of voltage-dependent K+ channels (KV), was studied on the resting vasomotor tone in porcine and human coronary arteries. Isolated coronary artery preparations were suspended in organ bath for isometric tension recordings. 4-AP (1.25x10-8 5.8x10-4 M) caused concentration-dependent contractions both in porcine and human coronary arteries. The EC50 values obtained with 4-AP did not differ significantly in porcine and human coronary… CONTINUE READING
1 Citations
24 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Similar Papers

Loading similar papers…