Humoral responses against coimmunized protein antigen but not against alphavirus-encoded antigens require alpha/beta interferon signaling.

@article{Hidmark2006HumoralRA,
  title={Humoral responses against coimmunized protein antigen but not against alphavirus-encoded antigens require alpha/beta interferon signaling.},
  author={Asa S Hidmark and Eva K. L. Nordstr{\"o}m and Pia Dosenovic and Mattias N. E. Forsell and Peter Liljestr{\"o}m and Gunilla B. Karlsson Hedestam},
  journal={Journal of virology},
  year={2006},
  volume={80 14},
  pages={7100-10}
}
Viruses typically elicit potent adaptive immune responses, and live-virus-based vaccines are among the most efficient human vaccines known. The mechanisms by which viruses stimulate adaptive immune responses are not fully understood, but activation of innate immune signaling pathways in the early phase of the infection may be of importance. In addition to stimulating immune responses to viral antigens expressed in infected cells, viruses can also provide adjuvant signals to coimmunized protein… CONTINUE READING

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