Humoral immunomodulatory effect of influenza vaccine in potential blood donors: implications for transfusion safety.

Abstract

BACKGROUND Generalised immune stimulation may follow vaccination causing increased antibody titres of nonvaccine-related antibodies or bystander antibodies, including those to human leukocyte antigens (HLA) and ABO blood group antigens. HLA antibodies may lead to transfusion-related acute lung injury. High-titre ABO antibodies may cause acute haemolytic… (More)
DOI: 10.1111/j.1365-3148.2011.01097.x

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