Humoral immunity to Borrelia burgdorferi N40 decorin binding proteins during infection of laboratory mice.

@article{Feng1998HumoralIT,
  title={Humoral immunity to Borrelia burgdorferi N40 decorin binding proteins during infection of laboratory mice.},
  author={Sunlian Feng and Emir Hodzic and Brian Stevenson and Stephen W. Barthold},
  journal={Infection and immunity},
  year={1998},
  volume={66 6},
  pages={2827-35}
}
A Borrelia burgdorferi N40 genomic expression library was screened with serum from actively infected mice to identify gene products that elicit protective immunity. A clone that contained a putative bicistronic operon containing two genes that encoded 20- and 22-kDa lipoproteins was identified and sequenced. These genes showed homology with the genes encoding decorin binding proteins DbpB and DbpA, respectively, of B. burgdorferi 297 and B31. N40-dbpA DNA hybridized with B. burgdorferi N40 DNA… CONTINUE READING
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Borrelia burgdorferi strainspecific OspC-mediated immunity in mice

  • L. K. Bockenstedt, E. Hodzic, +5 authors S. W. Barthold
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