Humoral immunity is not critical for protection against experimental infection with Sarcocystis neurona in B-cell-deficient mice.

@article{Witonsky2005HumoralII,
  title={Humoral immunity is not critical for protection against experimental infection with Sarcocystis neurona in B-cell-deficient mice.},
  author={Sharon G. Witonsky and Robert M. Gogal and Robert E. Duncan and Heather A. Norton and Dan A. Ward and Jibing Yang and David S. Lindsay},
  journal={The Journal of parasitology},
  year={2005},
  volume={91 4},
  pages={
          830-7
        }
}
Immunodeficient B-cell-deficient mice (mmuMT) were infected with Sarcocystis neurona merozoites to determine the role of B cells and the humoral immune response in protective immunity. As expected, the mice did not seroconvert based on a direct agglutination test. Infected mice did not have significant changes in gross pathology at the time points examined. Histologic changes included mild perivascular and peribronchial infiltrate in the lungs; perivascular infiltrate and mild inflammatory… CONTINUE READING
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