Humoral immune response to recombinant viral NS3 protein in patients with hepatitis C

Abstract

Full-length recombinant NS3 protein was used in a test system for detection of specific antibodies in the sera from patients with hepatitis C. Possible antigenic determinants in NS structure were predicted. It was demonstrated that serological analysis requires enzyme immunoassay with full-length NS3. 
DOI: 10.1007/s10517-005-0218-1

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