Humoral immune response to Aggregatibacter actinomycetemcomitans leukotoxin.

  title={Humoral immune response to Aggregatibacter actinomycetemcomitans leukotoxin.},
  author={Monica Brage and Anders B Holmlund and Anders Johansson},
  journal={Journal of periodontal research},
  volume={46 2},
BACKGROUND AND OBJECTIVE Periodontal disease is an inflammatory condition caused by bacterial infections that result in loss of the tooth supporting tissue. The periodontal pathogens produce virulence factors with capacity to affect the host immune response. Aggregatibacter actinomycetemcomitans is a periodontal pathogen that produces a leukotoxin that specifically affects human leukocytes. The aims of the present study were to examine the presence and function of systemic antibodies to the… CONTINUE READING
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