Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19

@article{Juno2020HumoralAC,
  title={Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19},
  author={J. Juno and H. Tan and W. Lee and A. Reynaldi and H. Kelly and K. Wragg and R. Esterbauer and H. Kent and C. Batten and F. Mordant and N. Gherardin and P. Pymm and M. Dietrich and N. Scott and W. Tham and D. Godfrey and K. Subbarao and M. Davenport and S. Kent and A. Wheatley},
  journal={Nature Medicine},
  year={2020},
  pages={1-7}
}
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has dramatically expedited global vaccine development efforts 1 – 3 , most targeting the viral ‘spike’ glycoprotein (S). S localizes on the virion surface and mediates recognition of cellular receptor angiotensin-converting enzyme 2 (ACE2) 4 – 6 . Eliciting neutralizing antibodies that block S–ACE2 interaction 7 – 9 , or indirectly prevent membrane fusion 10 , constitute an attractive modality for vaccine-elicited… Expand
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