Humans immunized with Streptococcus mutans antigens by mucosal routes.

  title={Humans immunized with Streptococcus mutans antigens by mucosal routes.},
  author={Noel K. Childers and Gary Tong and Feng-Lan Li and Ananda P. Dasanayake and Katharine Kirk and Suzanne M. Michalek},
  journal={Journal of dental research},
  volume={81 1},
Strategies aimed at the prevention of Streptococcus mutans infection and dental caries include mucosal immunization, which results in salivary anti-S. mutans responses. The purpose of this study was to evaluate the effectiveness of nasal vs. tonsillar immunization with S. mutans antigens in inducing salivary immune responses. Twenty-one adult subjects were immunized twice, within a seven-day interval, with a glucosyltransferase-enriched preparation (E-GTF) administered by nasal or tonsillar… CONTINUE READING

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