Humanization and simultaneous optimization of monoclonal antibody.

Abstract

Antibody humanization is an essential technology for reducing the potential risk of immunogenicity associated with animal-derived antibodies and has been applied to a majority of the therapeutic antibodies on the market. For developing an antibody molecule as a pharmaceutical at the current biotechnology level, however, other properties also have to be… (More)
DOI: 10.1007/978-1-62703-586-6_7

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