Humanin expression in skeletal muscles of patients with chronic progressive external ophthalmoplegia

Abstract

AbstractWe showed that humanin (HN), an endogenous peptide against Alzheimer disease-related insults, was expressed in muscles of patients with chronic progressive external ophthalmoplegia (CPEO), a major mitochondrial disease. Because HN was recently found to block proapoptotic Bax function and exert its versatile cytoprotective effects in association with… (More)
DOI: 10.1007/s10038-006-0397-2

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