Human venous hemodynamics in microgravity and prediction of orthostatic tolerance in flight

Abstract

The paper presents the results of investigating the lower limbs venous status in cosmonauts (n = 13) with the use of occlusion plethysmography in six-month missions to the Russian segment of International space station (ISS). An interrelation of shifts in venous capacitance, compliance and filling with orthostatic tolerance (OT) in the lower body negative pressure test (LBNP) was stated. OT predictability by the leg vein status in the course of space flight was demonstrated. The objective changes in veins predictive of OT reduction were identified. There are three levels of changes in venous capacitance, compliance and filling that prognosticate respective reductions LBNP tolerance and were attested in 91% of the in-flight LBNP testing.

DOI: 10.1134/S0362119715070063

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@article{Kotovskaya2013HumanVH, title={Human venous hemodynamics in microgravity and prediction of orthostatic tolerance in flight}, author={A . R . Kotovskaya and Galina Fomina}, journal={Human Physiology}, year={2013}, volume={41}, pages={699-703} }