Human uveal melanoma expresses NG2 immunoreactivity.

  title={Human uveal melanoma expresses NG2 immunoreactivity.},
  author={Yong Li and Michele C. Madigan and Kenneth Lai and Robert Max Conway and Frank A. Billson and Roger Crouch and Barry J. Allen},
  journal={The British journal of ophthalmology},
  volume={87 5},
BACKGROUND/AIMS NG2 is the rat homologue of the human melanoma proteoglycan (HMP), also known as the high molecular weight melanoma associated antigen. Most cutaneous melanomas, as well as glioblastomas, chondrosarcomas, and some leukaemias express NG2 immunoreactivity, recognised using monoclonal antibody (mAb) 9.2.27. This antibody has also been used for molecular targeting in targeted alpha therapy for melanoma. The purpose of this study was to evaluate the expression of NG2 immunoreactivity… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 12 extracted citations

Increased chondroitin sulphate proteoglycan expression (B5 immunoreactivity) in metastases of uveal melanoma.

Annals of oncology : official journal of the European Society for Medical Oncology • 2006
View 3 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 32 references

Similar Papers

Loading similar papers…