Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure.

@article{Liu2014HumanUC,
  title={Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure.},
  author={Zongcai Liu and Fanwei Meng and Chan Li and Xin Zhou and Xiao-Ping Zeng and Yixin He and Randall J Mrsny and Muyun Liu and Xiang Hu and Ji-Fan Hu and Tao Li},
  journal={Cytotherapy},
  year={2014},
  volume={16 9},
  pages={
          1207-19
        }
}
BACKGROUND AIMS Acute liver failure (ALF), a life-threatening disease characterized by the sudden loss of hepatic function, can occur after an accidental or intentional acetaminophen overdose. METHODS With the use of an ALF mouse model, we examined both the preventive and therapeutic potential of intravenously administered human umbilical cord-derived mesenchymal stromal cells (hUCMSCs). Primary hUCMSCs were purified from freshly collected full-term umbilical cords and intravenously… CONTINUE READING
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