Human umbilical cord mesenchymal stem cells reduce fibrosis of bleomycin-induced lung injury.

@article{Moodley2009HumanUC,
  title={Human umbilical cord mesenchymal stem cells reduce fibrosis of bleomycin-induced lung injury.},
  author={Yuben Moodley and Daniel M Atienza and Ursula Manuelpillai and Chrishan S. Samuel and Jorge Tchongue and Sivakami Ilancheran and Richard Boyd and Alan Trounson},
  journal={The American journal of pathology},
  year={2009},
  volume={175 1},
  pages={303-13}
}
Acute respiratory distress syndrome is characterized by loss of lung tissue as a result of inflammation and fibrosis. Augmenting tissue repair by the use of mesenchymal stem cells may be an important advance in treating this condition. We evaluated the role of term human umbilical cord cells derived from Wharton's jelly with a phenotype consistent with mesenchymal stem cells (uMSCs) in the treatment of a bleomycin-induced mouse model of lung injury. uMSCs were administered systemically, and… CONTINUE READING

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