Human umbilical cord-derived mesenchymal stem cells can secrete insulin in vitro and in vivo.

@article{Boroujeni2014HumanUC,
  title={Human umbilical cord-derived mesenchymal stem cells can secrete insulin in vitro and in vivo.},
  author={Zahra Boroujeni and Ahmad Aleyasin},
  journal={Biotechnology and applied biochemistry},
  year={2014},
  volume={61 2},
  pages={82-92}
}
Diabetes mellitus is characterized by autoimmune destruction of pancreatic beta cells, leading to decreased insulin production. Differentiation of mesenchymal stem cells (MSCs) into insulin-producing cells offers novel ways of diabetes treatment. MSCs can be isolated from the human umbilical cord tissue and differentiate into insulin-secreting cells. Human umbilical cord-derived stem cells (hUDSCs) were obtained after birth, selected by plastic adhesion, and characterized by flow cytometric… CONTINUE READING
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Generation of insulin ÇÉproducing cells from PDX ÇÉ1 gene ÇÉmodified human mesenchymal stem cells

  • Y Li, R Zhang, H Qiao
  • JOURNAL OF CELLULAR PHYSIOLOGY
  • 2007
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