Human umbilical cord-derived cells can often serve as feeder cells to maintain primate embryonic stem cells in a state capable of producing hematopoietic cells.

@article{Hiroyama2008HumanUC,
  title={Human umbilical cord-derived cells can often serve as feeder cells to maintain primate embryonic stem cells in a state capable of producing hematopoietic cells.},
  author={Takashi Hiroyama and Kazuhiro Sudo and Naoko Aoki and Kenichi Miharada and Inaho Danjo and Tsuyoshi Fujioka and Toshiro Nagasawa and Yukio Nakamura},
  journal={Cell biology international},
  year={2008},
  volume={32 1},
  pages={
          1-7
        }
}
Clinical application of human embryonic stem (ES) cells will require the establishment of methods for their culture, either in the presence or absence of human-derived feeder cells. We have tested the ability of non-immortalized cultured cells derived from human umbilical cord (HUC cells) to support ES cell culture. A primate ES cell line that had been established and maintained with mouse embryonic fibroblasts was cultured on HUC cells for >3 months (HUC-maintained ES cells). These cells… CONTINUE READING