Human umbilical cord blood cells protect against hypothalamic apoptosis and systemic inflammation response during heatstroke in rats.

@article{Liu2009HumanUC,
  title={Human umbilical cord blood cells protect against hypothalamic apoptosis and systemic inflammation response during heatstroke in rats.},
  author={Won-Shiung Liu and Chun-Ta Chen and Ning-Hui Foo and Hsuan-Rong Huang and Jhi-Joung Wang and Sheng-Hsien Chen and Tao Chen},
  journal={Pediatrics and neonatology},
  year={2009},
  volume={50 5},
  pages={208-16}
}
BACKGROUND Intravenous administration of human umbilical cord blood cells (HUCBC) has been shown to improve heatstroke by reducing arterial hypotension as well as cerebral ischemia and damage in a rat model. To extend these findings, we assessed both hypothalamic neuronal apoptosis and systemic inflammatory responses in the presence of HUCBCs or vehicle medium immediately after initiation of heatstroke. METHODS Anesthetized rats, immediately after the initiation of heat stress, were divided… CONTINUE READING

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