Human tumor models in the severe combined immune deficient (scid) mouse

@article{PaineMurrieta1997HumanTM,
  title={Human tumor models in the severe combined immune deficient (scid) mouse},
  author={Gillian D. Paine-Murrieta and Charles W. Taylor and Rebecca A. Curtis and Marialouisa H. A. Lopez and Robert T. Dorr and Cynthia S. Johnson and Carole Y. Funk and Floyd H. Thompson and Evan M. Hersh},
  journal={Cancer Chemotherapy and Pharmacology},
  year={1997},
  volume={40},
  pages={209-214}
}
Purpose: To test a number of established human tumor cell lines and early passage breast cancer (UACC2150) and melanoma cells (UACC1273) for growth in the scid mouse and the tumors' response to conventional chemotherapeutic drugs. Methods: Established melanoma (A375, C81-61), colon (SW480), lung (A549), lymphomoblastoid leukemia (LCL-B), promyelocytic leukemia (HL60), prostate (PC-3, DU145), and breast (MCF7) cell lines were injected at subcutaneous (s.c.), intraperitoneal (i.p.), or mammary… CONTINUE READING