Human tolerogenic DC-10: perspectives for clinical applications

  title={Human tolerogenic DC-10: perspectives for clinical applications},
  author={Giada Amodio and Silvia Gregori},
  booktitle={Transplantation research},
Dendritic cells (DCs) are critically involved in inducing either immunity or tolerance. During the last decades efforts have been devoted to the development of ad hoc methods to manipulate DCs in vitro to enhance or stabilize their tolerogenic properties. Addition of IL-10 during monocyte-derived DC differentiation allows the induction of DC-10, a subset of… CONTINUE READING

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