Human thyroid carcinoma cell lines show different retinoic acid receptor repertoires and retinoid responses.

@article{Schmutzler2004HumanTC,
  title={Human thyroid carcinoma cell lines show different retinoic acid receptor repertoires and retinoid responses.},
  author={Cornelia Schmutzler and Cuong Hoang-Vu and Barbara R{\"u}ger and Josef Koehrle},
  journal={European journal of endocrinology},
  year={2004},
  volume={150 4},
  pages={547-56}
}
OBJECTIVE Disturbed expression of retinoic acid (RA) receptors (RAR/RXR) contributes to the pathogenesis and tumor progression of epithelial carcinomas. DESIGN To examine whether altered responses to retinoids may correlate with differences in RA receptor equipment, retinoid effects were examined in human thyroid carcinoma cell lines of various differentiation stages in culture and after xenotransplantation onto rodent models. METHODS Cell growth was assessed by the MTT test, mRNA… CONTINUE READING

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