Human term placenta as a source of hematopoietic cells.

@article{Serikov2009HumanTP,
  title={Human term placenta as a source of hematopoietic cells.},
  author={Vladimir B. Serikov and Catherine Hounshell and Sandra Larkin and William Green and Hirokazu Ikeda and Mark C. Walters and Frans A. Kuypers},
  journal={Experimental biology and medicine},
  year={2009},
  volume={234 7},
  pages={813-23}
}
The main barrier to a broader clinical application of umbilical cord blood (UCB) transplantation is its limiting cellular content. Thus, the discovery of hematopoietic progenitor cells in murine placental tissue led us investigate whether the human placenta contains hematopoietic cells, sites of hematopoiesis, and to develop a procedure of processing and storing placental hematopoietic cells for transplantation. Here we show that the human placenta contains large numbers of CD34-expressing… CONTINUE READING

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Human term placenta as a source of hematopoietic stem cells

  • V Serikov, F. Kuypers
  • Cell Transplantation and Tissue Engineering
  • 2008
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