Human symbionts use a host-like pathway for surface fucosylation.

  title={Human symbionts use a host-like pathway for surface fucosylation.},
  author={Michael J. Coyne and Barbara Reinap and Martin M Lee and Laurie E. Comstock},
  volume={307 5716},
The mammalian intestine harbors a beneficial microbiota numbering approximately 10(12) organisms per gram of colonic content. The host tolerates this tremendous bacterial load while maintaining the ability to efficiently respond to pathogenic organisms. In this study, we show that the Bacteroides use a mammalian-like pathway to decorate numerous surface capsular polysaccharides and glycoproteins with l-fucose, an abundant surface molecule of intestinal epithelial cells, resulting in the… CONTINUE READING

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